Tumor microenvironment and immune cells.
Adapted from https://www.intechopen.com/
Cancer research focuses on the underlying genetic and epigenetic defects of the disease. Now, however, pharmaceutical companies are turning their attention to the tumor microenvironment (TME), a battlefield made up of elements around cancer cells. Research on the impact of tumor progression the discovery and development of effective cancer immunotherapy requires a better understanding of the tumor microenvironment. The composition of tumor microenvironment at different stages of cancer progression depends on physiology, immune system and related cellular and molecular factors. To dissect the various stages of tumorigenesis, from pathogenesis to cell transformation and metastasis, it is necessary to have a comprehensive understanding of the tumor microenvironment. Existing immunotherapies have been commercialized and have achieved great success, and common strategies may include, but are not limited to, antibody drugs, cell therapy, oncolytic viruses, and combination therapies. Creative Proteomics offers a wide range of antibody and immunoassay combinations to measure specific biomarkers, which can help researchers understand the process.
Cancer has many forms and unique molecular characteristics, and it is still difficult to study without appropriate tools. Protein identification and analysis is a key component of these efforts., Creative Proteomics has developed a comprehensive portfolio of products and solutions for cancer researchers.We provide a wide range of primary antibody choices for a variety of applications.
1. ELISA and multiple immunoassay were used to measure secreted proteins.
2. Western blotting. for detection of phosphorylated proteins and other post-translational modifications.
3. Fluorescence imaging and high content analysis for protein localization and visualization in cells, tumors and tissues.
Mature and reliable tumor microenvironment experimental analysis platform: rich project experience, participation in major projects, high-level cooperation results published.
Based on the analysis of high-quality data, the contents and methods of the analysis were pre-researched and tested, which is indeed mature and feasible.
Typical experimental process for preparation and detection of solid tumor samples
Creative Proteomics provides a wide range of antibody and immunoassay combinations to measure specific biomarkers, uses mature ELISA and multiplex immunoassays to measure secreted proteins, and Western blots can detect phosphorylated proteins and other post-translational modifications, fluorescence Imaging and high-content analysis for protein localization and visualization in tumors and tissues can help researchers better understand the tumor microenvironment.
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