Radiotherapy, chemotherapy and immune anti-tumor treatment can directly produce cytotoxicity or activate the immune response to change the composition of the intestinal flora and cause microecological disorders, which can have side effects on the intestinal barrier function. More and more studies have shown that the intestinal flora affects the therapeutic activity of antitumor drugs through pharmacodynamic and immunological mechanisms. It is of great significance to study and clarify the mechanism of clinical tumor treatment and intestinal flora changes and the antitumor efficacy of drugs.
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